api active pharmaceutical ingredient definition

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While PQQ appears to have numerous health benefits, individuals considering supplementation should approach it with care. The optimal dosage of PQQ has not been definitively established, and the effects can vary among individuals. It is advisable to consult with a healthcare professional before starting any new supplement, particularly for those with pre-existing health conditions or those taking medications.


While both PQQ and CoQ10 offer distinct benefits, their combination presents a unique opportunity for enhanced cellular health. PQQ’s ability to stimulate mitochondrial biogenesis, alongside CoQ10’s role in ATP production, creates a powerful synergy that can potentially maximize energy levels and cognitive function.


Moreover, PQQ is renowned for its potent antioxidant properties. Oxidative stress, which is an imbalance between free radicals and antioxidants in the body, is a major contributor to the development of numerous chronic conditions, including cardiovascular diseases, neurodegenerative disorders, and even cancer. PQQ helps neutralize free radicals, thereby reducing oxidative damage to cells and tissues. This protective effect may assist in mitigating the aging process and promoting healthier aging.


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d,l-α-Ketoisoleucine is a branched-chain amino acid derivative, characterized by its unique structure that features a keto group. This compound is essential for various metabolic processes, acting as a precursor for the synthesis of proteins and other vital biomolecules. When combined with calcium, a crucial mineral known for its role in bone health and cellular functions, d,l-α-ketoisoleucine forms a calcium salt that enhances its stability and bioavailability. The combination of these two compounds not only offers nutritional benefits but also improves the compound's solubility in biological systems, facilitating better absorption and utilization in the body.


PQQ is a redox cofactor, which means it participates in oxidation-reduction reactions, crucial processes in cellular metabolism. Discovered in 1964, this compound was first identified as a vitamin-like substance required by certain bacteria for growth. Over the decades, researchers have explored PQQ's role beyond microbes, recognizing its potential in human health as an essential element in mitochondrial function.


Research has shown that L-Ornithine L-Aspartate can be beneficial for liver health, particularly for individuals with liver dysfunction. The compound aids in the detoxification of ammonia, making it especially useful for patients with hepatic encephalopathy, a condition characterized by brain dysfunction due to liver failure. Studies suggest that LOLA can help lower blood ammonia levels, thereby improving overall cognitive function and quality of life for these patients. By supporting the urea cycle, LOLA helps the liver manage toxins more effectively, enabling it to perform better.


Ensuring an adequate intake of Vitamin C is crucial for reaping its benefits. Here are some excellent sources of this vital nutrient:

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